Website: Design in Progress...
 Join us  Support our cause INTL directors

   ​​SCIENTIFIC DRUG-FREE PREVENTION AND TREATMENT OF  DISEASES

A Non-Profit Medical Research Organization  with international scientists
from many countries working to serve humanity
- 501 (c) (3) Pending - 

www. apri-us.orgple text.

info@apri-us.orgple text.

Compare the Pharmacological actions between our innovative $25.00 PHYTOMEDICINE PREVENTIVE REMDY we created to stop COVID-19 infection  to the $1500
 ANTI-REPLICATION COVID-19 REMDESIVIR DRUG

In 2021, we formulated a BETA VERSION OF A SAFE AND EFFECTIVE REMEDY to neutralize COVID-19 infection using only PHYTO anti-viral ingredients. Users can self-treat at home. The treatment takes about 3-5 minutes each time, repeat every 30 to 60 minutes up to 8-10 times per day. The remedy works when applied within 1-3 days of infection at the first symptoms. During treatment, coughing and fever reduced within 1 day; Patients can eat and sleep normally. Most tested NEGATIVE in less than 2 days. As a contact-viral treatment, it does not matter which virus and will work against ANY respiratory viruses: CORONAVIRUS and INFLUENZA .

ACTION OR ISSUES REMDESIVIR OR SIMILAR ANTIVIRAL DRUGS OUR CHEMICAL-FREE NATURAL PHYTOMEDICINE
HOW THE MEDICATION IS DESIGNED TO KILL OR NEUTRALIZE THE TARGET RESPIRATORY VIRUS Remdesivir ​ inhibits viral replication by targeting the RNA-dependent RNA polymerase (RdRp) enzyme, preventing the complete RNA strand process and cannot act in earlier transcription stage. This allows more virus escape or unaffected. To be effective, higher dosage must be use and this can KILL THE PATIENT. Our​ drug-free remedy targets the virus at earlier stage at the mucosal epithelium when virus are weak, not yet with proteins from human cells, thereby we can kill them in mass quantity by trapping  them inside the thousands of medicated particles. If treated in the 1st 3 days of infection, most virus are killed. Even some escaped, they are already weakened or incomplete to cause damage.
WHAT ADVANTAGES WHEN ATTACK THE VIRUS BEFORE THEY ENTER THE INNER CELLS TO ACQUIRE HUMAN GENETIC MATERIALS? Remdesivir  is a nucleotide analog prodrug, formula was originally an antiviral drug  for slow acting hepatitis C Ebola, then modified for COVID-19. The core of remdesivir based on (GS-441524 then to GS-441524). The drug  attacks ONLY viral transcription completed and this can cause MASSIVE COLLATERAL DAMAGE to lung cells. This design is NOT practical and not effective for today's fast acting respiratory virus. To stop virus ability to enter human cells to acquire human DNA for replication is most effective to kill and stop infection also reduce immune overload and prevent inflammation, with minimized healthy virus for transmission, minimal damaged cells; Stopping them at this stage preserve healthy cells that may cause cancers later. Neutralizing antibodies BEFORE entry are best antiviral defense
With COVID-19, INFLUENZA, CHILDREN, ELDERLY, persons w/ other  conditions are vulnerable.  ANTI-VIRAL drugs are not workable for them. REMDESIVIR  originally made for Hepatitis C, Ebola in adults with no other health problems.  Even in healthy adults, ELEVATED LIVER ENZYMES and HEPATOXICITY. Other antiviral drugs with sulfobutylether-β-cyclodextrin (SBECD) can impair kidney function and collateral liver metabolism problem. NO COVID-19 DRUGS at least up to 2024 was intended for children and elders. 

We purposely design our remedy as a LOCAL ACTION so CHILDREN, ELDERS and SICK PATIENTS are free to use. In contrast, most antiviral drugs are systemic: Nucleoside Analogues (e.g., acyclovir, zidovudine) Protease Inhibitors (e.g., ritonavir, lopinavir)  and REMDESIVIR (via cytochrome P450 enzymes): Other drugs are kidney-processed (Cidofovir). From a pharmacological view, our design is much more practical and SAFE.
in a PANDEMIC with massive people infected, can we realistically rely on the current anti-viral drugs? DEFINITELY NOT. Pandemic situation requires more practical solution that drugs will cause: Collateral problems to organs, cost of medication, cost to administer and manage problems when resources are limited. Phytomedicine does not pose such problems. Pandemic or epidemic situation requires immediate results with least cost so more can be treated, least collateral damages to so least resources can be spread out fast enough to cover more people especially the most vulnerable groups: CHILDREN, ELDERS and the SICK. Conventional drugs cannot handle them or effective enough at the heavy cost.

The above advantages illustrate the practicality, efficiency and benefits of typical PREVENTIVE TREATMENT for emergency epidemic situation of any respiratory viruses.  When phytomedicine is correctly and wisely formulated,  it is most effective especially for remote, rural and poor countries without adequate facility and staff for many urgent pressure against a spreading epidemic.

Let's examine and compare the MECHANISMS OF ACTION of the high costr ANTI-VIRAL DRUGS
and our low cost SIMPLE, DIRECT, DRUG-FREE PHYTOMEDICINE that neutralize viruses in 1-2 days 

can Phytomedicine kill deadly viruses 
like Covid-19, Influenza, swine or 
Bird Flu like drugs?

Each antiviral drug is designed to attack the specific virus in a specific mode of killing. For example, REMDESIVIR prevents virus from replication; TAMIFLU is to inhibit neuraminidase after replication.  Our Plant-based antiviral  substance cannot kill but will attach to the spike proteins, weaken  or disrupt their ability to move, to feed or to enter human cells thus die in hours!

As plant derivatives, ingredients are edible so no side effects. Anti-viral actions ARE LOCALIZED to upper respiratory area. Unused ingredients are naturally metabolized by the body like any food. We use 6 different phyto ingredients with an table-top electric device . This treatment was tested on 32 persons  with Covid-19 within the 1st 1-2 days with symptoms. Viruses incubated in the upper ​respiratory tracts were neutralized in 24-48 hours. Patients can relax, eat and sleep normally . Cost just  $30 for the medication and device. But can be used for the whole family for months!

Practical, Fast, Simple, Home-usable and effective to control epidemics and save lives!

An Overview of the Viral Pathogenesis relative to the Pharmacological action of Systemic Anti-Viral Drugs in comparison with our 
Simple but Direct Action Phyto Anti-viral remedy

COMPARE USAGE PRACTICALITY AND EFFICACY BETWEEN DRUGS AND PHTYTOMEDICNE

 

TYPICAL ACTION ANTI-VIRAL DRUGS OUR  PHYTOMEDICINE
HOW MEDICATION IS USED ORAL, SYSTEMIC via LIVER
HOW LONG FOR DRUG TO CONTACT WITH VIRUS Systemic​ drug is highly inefficient and slow
EFFICACY, POTENCY at contact with virus REDUCED EFFICACY to at least 70%
SIDE EFFECTS TO LIVER ANTIVIRAL PRODRUGS ARE HIGH RISK TO LIVER

Our delivery and application method is localized, concentrated, more efficient

Inhaled millions of micro droplets with antiviral agents to bind to virus from sinus to respiratory tracts 

CONTACT MEDICATION in droplet forms are more efficient and will bind with virus INSTANTLY to start working

Immediate pharmacological action is necessary against respiratory virus

RESULTS

As PRODRUG, Remdesivir SHOULD NOT BE PROCESSED BY LIVER, TAMIFLU efficacy is reduced to at least 20%

As droplets, bioavailability is 90%+ when  contact with virus: Hi Efficacy

Most antiviral drugs are PRODRUG are high risk of LIVER TOXICITY

Our concentration is too small to pose risks but effective against virus

COMPARE ANTIVIRAL EFFICACY ACTIONS BETWEEN DRUGS AND OUR PHYTOMEDICINE

RESULTS

TYPICAL ACTION ANTI-VIRAL DRUGS OUR  PHYTOMEDICINE
HOW MEDICATION IS USED ORAL, SYSTEMIC via LIVER
HOW LONG FOR DRUG TO CONTACT WITH VIRUS Systemic​ drug is highly inefficient and slow
EFFICACY, POTENCY at contact with virus REDUCED EFFICACY to at least 70%
SIDE EFFECTS TO LIVER ANTIVIRAL PRODRUGS ARE HIGH RISK TO LIVER
TYPICAL ACTION ANTI-VIRAL DRUGS OUR  PHYTOMEDICINE                    
% PEOPLE ACCESS TO DRUGS ONLY 50% OF INSURED AND HOSPITALIZED
ACTUAL RECOVERY FROM THOSE GIVEN THE DRUGS REMDESIVIR is less than 15%; TAMIFLU is 70%
COST PER DOSE $1500 for REMDESIVIR and $160-$250 for TAMIFLU
HOW FAST ONE CAN BE TREATED? PRESCRIPTIONS take tme to processed

In an epidemic or pandemic, the more people can be treated, the best chance to stop the spread

CHEAP ENOUGH FOR PEOPLE TO BUY or for government to distribute so ALL PEOPLE can use

IF TREATED WITH 1 DAY OF INFECTION SYMPTOMS, RECOVERY IS OVER 90%

Results are due to its SIMPLE, FAST and DIRECT CONTACT treatment

COST LESS THAN $50 BUT THE WHOLE FAMILY CAN USE FOR MANY MONTHS!

ANTIVIRAL DRUGS are fast moving. Cost too much is not the way to fight pandemic

DESIGNED FOR HOME USE, CHILDREN NO PROBLEM

HOME USE and easily available is much more useful against pandemic

RESULTS

NOTE: To prevent misunderstanding, medical info above are for general public are limited to what are practical or useful only. Scientific info are too lengthy to list here.

THE FUTURE PREVENTIVE TREATMENT FORMULA WE WANT TO DEVELOP AND READY FOR USE IN THE EVENT OF AN EMERGENCY OUTBREAK OF ANY EPIDEMICS OF SIMLAR RESPIRATORY VIRUSES​ LIKE COVID-19 OR INFLUENZA

With your support, our scientists can expand and improve on our formula above to use on the following deadly respiratory viruses immediately so we can be prepared and to stop any epidemics

RESPIRATORY VIRUS A

INFLUENZA A/B

Latest CDC report, influenza caused 27,000 deaths and 610,000 hospitalized in the U.S. this season. Globally, about 700,000 deaths with 47 million illnesses and . WE HOPE TO STUDY TO EXPAND AND IMPROVE ON OUR COVID-19 TREATMENT TO INFLUENZA. 
We expect the cost to be LESS THAN $15 PER TREATMENT

RESPIRATORY VIRUS b

SWINE FLU

H5N1, H7N9

Current drugs are Oseltamivir (Tamiflu),  Zanamivir (Relenza), Peramivir (Rapivab) ,  Baloxavir (Xofluza); There are sporadic infection on humans in rural area, most are of H3N2. WE LIKE TO DEVELOP DRUG-FREE TREATMENT ON HUMANS ASAP.

RESPIRATORY VIRUS C

BIRD FLU 
H5N1, H7N9

Recent outbreaks of bird flu (avian influenza) affecting millions of chicken farms and egg production. Signs of BIRD FLU have been known for years since Covid-19 but NOBODY in the US seem to do anything about it. WE CAN DEVELOP PREVENTIVE TREATMENT FOR BIRD FLU
ON BOTH FARMED CHICKENS and PEOPLE TO PREVENT AN EPIDEMIC.

RESPIRATORY VIRUS D

Respiratory Virus for animals

We plan to develop NON-CHEMCIAL PREVENTIVE TREATMENT FOR ANIMALS IN THE FORM OF FOGGING OR MIST SPRAYS. Chemical-free treatments are SAFER AND PREFERRED by both FARMERS and surrounding RESIDENTS. Such treatments will prevent any zoonotic events to humans.

Respiratory viruses can become a serious epidemic to both HUMANS and ANIMALS and disease prevention must be developed to protect both. CHEMICAL-FREE RESPIRATORY  PREVENTIVE TREATMENT FOR D0MESTIC AND FARMED ANIMALS IS CRITICAL TO OUR FOOD SUPPLY AND TO MINIMIZE THE RISKS OF ZOONOTICS IN HUMANS.